Main Article Content
Abstract
Ultraviolet (UV) radiation is a critical environmental stressor that accelerates oxidative damage, photoaging, and elevates the risk of skin malignancies. Although conventional sunscreens remain widely used, their drawbacks—including chemical safety concerns, limited photostability, and ecological impact—have intensified the search for natural alternatives. This study conducts a bibliometric exploration of natural photoprotective agents in cosmetic science, analysing publications from 2020 to 2025 indexed in Scopus. Using VOSviewer for co‑word mapping, 66 studies were examined to reveal thematic trends and highlight emerging compounds. The analysis points to the rising significance of polyphenols alongside marine-derived resources like seaweed. These agents are increasingly recognized for their antioxidant, anti-inflammatory, UV-protective, and pigmentation-modulating properties. Keyword clustering further illustrates the interdisciplinary nature of this research, linking cosmetic applications with toxicological and natural product studies, and emphasizing the balance between efficacy and safety. Overall, the findings indicate that polyphenols are increasingly recognized as sustainable, multifunctional ingredients poised to shape the future of cosmetic formulations.
Keywords
Article Details
References
- Al-sadek, T. and Yusuf, N. (2024) ‘Ultraviolet Radiation Biological and Medical Implications’, pp. 1924–1942.
- Ali, A. and Omer, A. (2025) ‘Mapping the Use of Bibliometric Software and Methodological Transparency in Literature Review Studies : A Comparative Analysis of China-Affiliated and Non-China-Affiliated Research Communities ( 2015 – 2024 )’.
- Amaro-ortiz, A., Yan, B. and Orazio, J.A.D. (2014) ‘Ultraviolet Radiation, Aging and the Skin: Prevention of Damage by Topical cAMP Manipulation’, pp. 6202–6219. Available at: https://doi.org/10.3390/molecules19056202.
- Androm, W. et al. (2024) ‘Would Rutin be a Feasible Strategy for Environmental-Friendly Photoprotective Samples ? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems’.
- Antonoaea, P. et al. (2025) ‘Multi-Active Cosmeceutical Formulations : Stability , Sensory Performance , and Skin Tolerability’.
- Bhattacharjee, D. et al. (2021) ‘A comparison of Natural and Synthetic Sunscreen Agents : A Review’, 13(1), pp. 3494–3505.
- Cadar, E. et al. (2025) ‘Bioactive Compounds of Marine Algae and Their Potential Health and Nutraceutical Applications : A Review’.
- Chavda, V.P. et al. (2023) ‘Journal of Drug Delivery Science and Technology Sunscreens : A comprehensive review with the application of nanotechnology’, Journal of Drug Delivery Science and Technology, 86(June), p. 104720. Available at: https://doi.org/10.1016/j.jddst.2023.104720.
- Chinjoo, N. and Golzary, A. (2025) ‘Microalgae : revolutionizing skin repair and enhancement’, Biotechnology Reports, 47(August), p. e00911. Available at: https://doi.org/10.1016/j.btre.2025.e00911.
- Du, Q. et al. (2024) ‘Protocol Protocol for conducting bibliometric analysis in biomedicine and related research using CiteSpace and VOSviewer software Protocol for conducting bibliometric analysis in biomedicine and related research using CiteSpace and VOSviewer software’, STAR Protocols, 5(3), p. 103269. Available at: https://doi.org/10.1016/j.xpro.2024.103269.
- Fonseca, S., Amaral, M.N. and Reis, C.P. (2023) ‘Marine Natural Products as Innovative Cosmetic Ingredients’, pp. 1–23.
- Gęgotek, A. et al. (2019) ‘Rutin and ascorbic acid cooperation in antioxidant and antiapoptotic effect on human skin keratinocytes and fibroblasts exposed to UVA and UVB radiation’, Archives of Dermatological Research, 311(3), pp. 203–219. Available at: https://doi.org/10.1007/s00403-019-01898-w.
- Giacomo, B. et al. (2020) ‘Development of an Innovative and Eco-Friendly UV Radiation Absorber, Based on Furan Moieties’, Cosmetics, pp. 1–13.
- Girsang, E. et al. (2020) ‘Antioxidant and antiaging activity of rutin and caffeic acid’, 10(2), pp. 147–156. Available at: https://doi.org/10.12928/pharmaciana.v10i2.13010.
- Górska-ponikowska, M. (2022) ‘Sunscreen cosmetics as basic protection against photoaging’, 11, pp. 225–230.
- Goswami, P.K., Samant, M. and Srivastava, R. (2013) ‘Review Article Natural Sunscreen Agents : A Review’, 2(6), pp. 458–463.
- Gromkowska-, K.J. et al. (2021) ‘The impact of ultraviolet radiation on skin photoaging — review of in vitro studies’, (December 2020), pp. 3427–3431. Available at: https://doi.org/10.1111/jocd.14033.
- Hartati, I. and Paramita, V. (2023) ‘Apocarotenoids: Sources, Classification and Their Potential Application as Food Additives’, Research in Chemical Engineering (RiCE), 2(2), pp. 44–50. Available at: https://doi.org/10.30595/rice.v2i2.112.
- Kim, K. et al. (2025) ‘The Antioxidant and Skin-Brightening Effects of a Novel Caffeic Acid Derivative , Caffeic Acid-3 , 4-Dihydroxyphenylpropanolester’, pp. 1–19.
- Kirby, A. (2023) ‘Exploratory Bibliometrics : Using VOSviewer as a Preliminary Research Tool’.
- Kosasih, K., Yulyana, A. and Dewi, C. (2025) ‘Green cosmeceuticals : design and evaluation of environmentally-friendly sunscreens with Vaccinium varingiaefolium leaf bioactives’, (Boo 2020), pp. 1–12. Available at: https://doi.org/10.3897/pharmacia.72.e160798.
- Lin, T.C. et al. (2022) ‘A Co-word Analysis of Selected Science Education Literature: Identifying Research Trends of Scaffolding in Two Decades (2000–2019)’, Frontiers in Psychology, 13(February), pp. 1–14. Available at: https://doi.org/10.3389/fpsyg.2022.844425.
- Lopez-polo, J. et al. (2024) ‘Effect of the incorporation of liposomes loaded with rutin on the transport properties of edible film produced with hydroxypropyl methylcellulose : An in vitro release study’, LWT, 191(November 2023), p. 115583. Available at: https://doi.org/10.1016/j.lwt.2023.115583.
- Maharani, F. and Hartati, I. (2023) ‘A Brief Review and Its Incorporation with Bibliometric Analysis of Phase Change Materials for Thermal Energy Storage’, Research In Chemical Engineering (RiCE), 2(1), pp. 01–07. Available at: https://doi.org/10.30595/rice.v2i1.64.
- Milutinov, J. (2024) ‘The Potential of Natural Compounds in UV Protection Products’.
- Mita, S.R. et al. (2025) ‘Catechins as Antimicrobial Agents and Their Contribution to Cosmetics’, pp. 1–12.
- Musielak, E. and Krajka-ku, V. (2024) ‘Liposomes and Ethosomes : Comparative Potential in Enhancing Skin Permeability for Therapeutic and Cosmetic Applications’.
- Nitulescu, G. et al. (2023) ‘Ultraviolet Filters for Cosmetic Applications’.
- Nurjanah et al. (2020) ‘Characterization and formulation of sunscreen from seaweed Padina australis and Euchema cottonii slurry Characterization and formulation of sunscreen from seaweed Padina australis and Euchema cottonii slurry’, pp. 0–9. Available at: https://doi.org/10.1088/1755-1315/404/1/012051.
- Pangestuti, R., Siahaan, E.A. and Kim, S.-K. (2018) ‘Photoprotective Substances Derived from Marine Algae’, Marine Drugs [Preprint]. Available at: https://doi.org/10.3390/md16110399.
- Portilho, L., Aiello, L.M. and Vasques, L.I. (no date) ‘Effectiveness of sunscreens and factors influencing sun protection : a review’.
- Rosic, N. et al. (2023) ‘Exploring Mycosporine-like Amino Acid UV-Absorbing Natural Products for a New Generation of Environmentally Friendly Sunscreens’.
- Sasounian, R. et al. (2024) ‘clean technologies Innovative Approaches to an Eco-Friendly Cosmetic Industry : A Review of Sustainable Ingredients’, pp. 176–198.
- Sguizzato, M. et al. (2026) ‘Supramolecular nanosystems for rutin topical application’, pp. 1–12.
- Shah, Y. and Mewada, R. (2023) ‘Recent advances in sunscreen agents and their formulations : A review’, 9(4), pp. 141–150.
- Shin, N. et al. (2022) ‘Plant polyphenols as green sunscreen ingredients : A systematic review’, (May), pp. 1–36. Available at: https://doi.org/10.1111/jocd.15170.
- Silva, A. and Plaine, A.H. (2023) ‘Electrochemical corrosion study of biomaterials: A bibliometric study based on co-word analysis’, Results in Engineering, 20(October), p. 101489. Available at: https://doi.org/10.1016/j.rineng.2023.101489.
- Singh, H. et al. (2025) ‘Dietary phytochemicals alleviate the premature skin aging : A comprehensive review’, Experimental Gerontology, 199(November 2024), p. 112660. Available at: https://doi.org/10.1016/j.exger.2024.112660.
- Sogan, A. et al. (2025) ‘Journal of Photochemistry & Photobiology , B : Biology Polyphenol-rich green propolis extract improves antioxidant and UV protection in sunscreen formulations’, 273(October). Available at: https://doi.org/10.1016/j.jphotobiol.2025.113284.
- Sulastri, N. et al. (2023) ‘Karakteristik sediaan krim tabir surya bubur rumput laut ( Turbinaria conoides ) dan ekstrak lengkuas ( Alpinia galanga ) [ Caracteristics of sunscreen from seaweed porridge ( Turbinaria conoides ) and galangal extract ( Alpinia galangal )]’, 5(1). Available at: https://doi.org/10.51179/jipsbp.v5i1.1945.
- Sumali, S.M. (2023) ‘A comparative study of UVA and UVB radiation : Mechanisms of DNA damage and repair’, 17(1), pp. 239–243. Available at: https://doi.org/10.15562/ijbs.v17i1.485.
- Tang, X. et al. (2024) ‘Current insights and future perspectives of ultraviolet radiation ( UV ) exposure : Friends and foes to the skin and beyond the skin’, Environment International, 185(November 2023), p. 108535. Available at: https://doi.org/10.1016/j.envint.2024.108535.
- Tanveer, M.A., Rashid, H. and Tasduq, S.A. (2023) ‘Heliyon Molecular basis of skin photoaging and therapeutic interventions by plant-derived natural product ingredients : A comprehensive review’, Heliyon, 9(3), p. e13580. Available at: https://doi.org/10.1016/j.heliyon.2023.e13580.
- Umam, M.M., Pringgenies, D. and Sedjati, S. (2025) ‘The potential of seaweed extracts from Suli Beach , Central Maluku : Antioxidant and photoprotective activities for natural cosmetic applications’, 27(03), pp. 86–92.
- Vost, J. et al. (2019) ‘Skin Protective Activity of Silymarin and its Flavonolignans’, pp. 1–12. Available at: https://doi.org/10.3390/molecules24061022.
- Wisudyaningsih, B., Barikah, K.Z. and Kamelia, I.N. (2025) ‘Effect of Quercetin and Zinc Oxide Concentrations on pH and In Vitro Activity of Sunscreen Lipstick’, Borneo Journal of Pharmacy, 8(2), pp. 167–175. Available at: https://doi.org/10.33084/bjop.v8i2.6797.
- Wisudyaningsih, B., Zu, K. and Lita, F.I. (2023) ‘Effect of Quercetin and Avobenzone Concentration on Physical Characteristics and In Vitro Activity of Sunscreen’, pp. 333–339. Available at: https://doi.org/10.25077/jsfk.10.3.333-339.2023.
References
Al-sadek, T. and Yusuf, N. (2024) ‘Ultraviolet Radiation Biological and Medical Implications’, pp. 1924–1942.
Ali, A. and Omer, A. (2025) ‘Mapping the Use of Bibliometric Software and Methodological Transparency in Literature Review Studies : A Comparative Analysis of China-Affiliated and Non-China-Affiliated Research Communities ( 2015 – 2024 )’.
Amaro-ortiz, A., Yan, B. and Orazio, J.A.D. (2014) ‘Ultraviolet Radiation, Aging and the Skin: Prevention of Damage by Topical cAMP Manipulation’, pp. 6202–6219. Available at: https://doi.org/10.3390/molecules19056202.
Androm, W. et al. (2024) ‘Would Rutin be a Feasible Strategy for Environmental-Friendly Photoprotective Samples ? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems’.
Antonoaea, P. et al. (2025) ‘Multi-Active Cosmeceutical Formulations : Stability , Sensory Performance , and Skin Tolerability’.
Bhattacharjee, D. et al. (2021) ‘A comparison of Natural and Synthetic Sunscreen Agents : A Review’, 13(1), pp. 3494–3505.
Cadar, E. et al. (2025) ‘Bioactive Compounds of Marine Algae and Their Potential Health and Nutraceutical Applications : A Review’.
Chavda, V.P. et al. (2023) ‘Journal of Drug Delivery Science and Technology Sunscreens : A comprehensive review with the application of nanotechnology’, Journal of Drug Delivery Science and Technology, 86(June), p. 104720. Available at: https://doi.org/10.1016/j.jddst.2023.104720.
Chinjoo, N. and Golzary, A. (2025) ‘Microalgae : revolutionizing skin repair and enhancement’, Biotechnology Reports, 47(August), p. e00911. Available at: https://doi.org/10.1016/j.btre.2025.e00911.
Du, Q. et al. (2024) ‘Protocol Protocol for conducting bibliometric analysis in biomedicine and related research using CiteSpace and VOSviewer software Protocol for conducting bibliometric analysis in biomedicine and related research using CiteSpace and VOSviewer software’, STAR Protocols, 5(3), p. 103269. Available at: https://doi.org/10.1016/j.xpro.2024.103269.
Fonseca, S., Amaral, M.N. and Reis, C.P. (2023) ‘Marine Natural Products as Innovative Cosmetic Ingredients’, pp. 1–23.
Gęgotek, A. et al. (2019) ‘Rutin and ascorbic acid cooperation in antioxidant and antiapoptotic effect on human skin keratinocytes and fibroblasts exposed to UVA and UVB radiation’, Archives of Dermatological Research, 311(3), pp. 203–219. Available at: https://doi.org/10.1007/s00403-019-01898-w.
Giacomo, B. et al. (2020) ‘Development of an Innovative and Eco-Friendly UV Radiation Absorber, Based on Furan Moieties’, Cosmetics, pp. 1–13.
Girsang, E. et al. (2020) ‘Antioxidant and antiaging activity of rutin and caffeic acid’, 10(2), pp. 147–156. Available at: https://doi.org/10.12928/pharmaciana.v10i2.13010.
Górska-ponikowska, M. (2022) ‘Sunscreen cosmetics as basic protection against photoaging’, 11, pp. 225–230.
Goswami, P.K., Samant, M. and Srivastava, R. (2013) ‘Review Article Natural Sunscreen Agents : A Review’, 2(6), pp. 458–463.
Gromkowska-, K.J. et al. (2021) ‘The impact of ultraviolet radiation on skin photoaging — review of in vitro studies’, (December 2020), pp. 3427–3431. Available at: https://doi.org/10.1111/jocd.14033.
Hartati, I. and Paramita, V. (2023) ‘Apocarotenoids: Sources, Classification and Their Potential Application as Food Additives’, Research in Chemical Engineering (RiCE), 2(2), pp. 44–50. Available at: https://doi.org/10.30595/rice.v2i2.112.
Kim, K. et al. (2025) ‘The Antioxidant and Skin-Brightening Effects of a Novel Caffeic Acid Derivative , Caffeic Acid-3 , 4-Dihydroxyphenylpropanolester’, pp. 1–19.
Kirby, A. (2023) ‘Exploratory Bibliometrics : Using VOSviewer as a Preliminary Research Tool’.
Kosasih, K., Yulyana, A. and Dewi, C. (2025) ‘Green cosmeceuticals : design and evaluation of environmentally-friendly sunscreens with Vaccinium varingiaefolium leaf bioactives’, (Boo 2020), pp. 1–12. Available at: https://doi.org/10.3897/pharmacia.72.e160798.
Lin, T.C. et al. (2022) ‘A Co-word Analysis of Selected Science Education Literature: Identifying Research Trends of Scaffolding in Two Decades (2000–2019)’, Frontiers in Psychology, 13(February), pp. 1–14. Available at: https://doi.org/10.3389/fpsyg.2022.844425.
Lopez-polo, J. et al. (2024) ‘Effect of the incorporation of liposomes loaded with rutin on the transport properties of edible film produced with hydroxypropyl methylcellulose : An in vitro release study’, LWT, 191(November 2023), p. 115583. Available at: https://doi.org/10.1016/j.lwt.2023.115583.
Maharani, F. and Hartati, I. (2023) ‘A Brief Review and Its Incorporation with Bibliometric Analysis of Phase Change Materials for Thermal Energy Storage’, Research In Chemical Engineering (RiCE), 2(1), pp. 01–07. Available at: https://doi.org/10.30595/rice.v2i1.64.
Milutinov, J. (2024) ‘The Potential of Natural Compounds in UV Protection Products’.
Mita, S.R. et al. (2025) ‘Catechins as Antimicrobial Agents and Their Contribution to Cosmetics’, pp. 1–12.
Musielak, E. and Krajka-ku, V. (2024) ‘Liposomes and Ethosomes : Comparative Potential in Enhancing Skin Permeability for Therapeutic and Cosmetic Applications’.
Nitulescu, G. et al. (2023) ‘Ultraviolet Filters for Cosmetic Applications’.
Nurjanah et al. (2020) ‘Characterization and formulation of sunscreen from seaweed Padina australis and Euchema cottonii slurry Characterization and formulation of sunscreen from seaweed Padina australis and Euchema cottonii slurry’, pp. 0–9. Available at: https://doi.org/10.1088/1755-1315/404/1/012051.
Pangestuti, R., Siahaan, E.A. and Kim, S.-K. (2018) ‘Photoprotective Substances Derived from Marine Algae’, Marine Drugs [Preprint]. Available at: https://doi.org/10.3390/md16110399.
Portilho, L., Aiello, L.M. and Vasques, L.I. (no date) ‘Effectiveness of sunscreens and factors influencing sun protection : a review’.
Rosic, N. et al. (2023) ‘Exploring Mycosporine-like Amino Acid UV-Absorbing Natural Products for a New Generation of Environmentally Friendly Sunscreens’.
Sasounian, R. et al. (2024) ‘clean technologies Innovative Approaches to an Eco-Friendly Cosmetic Industry : A Review of Sustainable Ingredients’, pp. 176–198.
Sguizzato, M. et al. (2026) ‘Supramolecular nanosystems for rutin topical application’, pp. 1–12.
Shah, Y. and Mewada, R. (2023) ‘Recent advances in sunscreen agents and their formulations : A review’, 9(4), pp. 141–150.
Shin, N. et al. (2022) ‘Plant polyphenols as green sunscreen ingredients : A systematic review’, (May), pp. 1–36. Available at: https://doi.org/10.1111/jocd.15170.
Silva, A. and Plaine, A.H. (2023) ‘Electrochemical corrosion study of biomaterials: A bibliometric study based on co-word analysis’, Results in Engineering, 20(October), p. 101489. Available at: https://doi.org/10.1016/j.rineng.2023.101489.
Singh, H. et al. (2025) ‘Dietary phytochemicals alleviate the premature skin aging : A comprehensive review’, Experimental Gerontology, 199(November 2024), p. 112660. Available at: https://doi.org/10.1016/j.exger.2024.112660.
Sogan, A. et al. (2025) ‘Journal of Photochemistry & Photobiology , B : Biology Polyphenol-rich green propolis extract improves antioxidant and UV protection in sunscreen formulations’, 273(October). Available at: https://doi.org/10.1016/j.jphotobiol.2025.113284.
Sulastri, N. et al. (2023) ‘Karakteristik sediaan krim tabir surya bubur rumput laut ( Turbinaria conoides ) dan ekstrak lengkuas ( Alpinia galanga ) [ Caracteristics of sunscreen from seaweed porridge ( Turbinaria conoides ) and galangal extract ( Alpinia galangal )]’, 5(1). Available at: https://doi.org/10.51179/jipsbp.v5i1.1945.
Sumali, S.M. (2023) ‘A comparative study of UVA and UVB radiation : Mechanisms of DNA damage and repair’, 17(1), pp. 239–243. Available at: https://doi.org/10.15562/ijbs.v17i1.485.
Tang, X. et al. (2024) ‘Current insights and future perspectives of ultraviolet radiation ( UV ) exposure : Friends and foes to the skin and beyond the skin’, Environment International, 185(November 2023), p. 108535. Available at: https://doi.org/10.1016/j.envint.2024.108535.
Tanveer, M.A., Rashid, H. and Tasduq, S.A. (2023) ‘Heliyon Molecular basis of skin photoaging and therapeutic interventions by plant-derived natural product ingredients : A comprehensive review’, Heliyon, 9(3), p. e13580. Available at: https://doi.org/10.1016/j.heliyon.2023.e13580.
Umam, M.M., Pringgenies, D. and Sedjati, S. (2025) ‘The potential of seaweed extracts from Suli Beach , Central Maluku : Antioxidant and photoprotective activities for natural cosmetic applications’, 27(03), pp. 86–92.
Vost, J. et al. (2019) ‘Skin Protective Activity of Silymarin and its Flavonolignans’, pp. 1–12. Available at: https://doi.org/10.3390/molecules24061022.
Wisudyaningsih, B., Barikah, K.Z. and Kamelia, I.N. (2025) ‘Effect of Quercetin and Zinc Oxide Concentrations on pH and In Vitro Activity of Sunscreen Lipstick’, Borneo Journal of Pharmacy, 8(2), pp. 167–175. Available at: https://doi.org/10.33084/bjop.v8i2.6797.
Wisudyaningsih, B., Zu, K. and Lita, F.I. (2023) ‘Effect of Quercetin and Avobenzone Concentration on Physical Characteristics and In Vitro Activity of Sunscreen’, pp. 333–339. Available at: https://doi.org/10.25077/jsfk.10.3.333-339.2023.