AKTIVITAS ANTIBAKTERI SALEP EKSTRAK DAUN SUKUN (Artocarpus altilis) DENGAN DUA MACAM KOMBINASI BASIS SALEP TERHADAP BAKTERI Stapylococcus aureus

Abstract

ABSTRACT
Breadfruit leaves (Artocarpus altilis) was contain compound of flavonoids, tannins and phenol that
the ability as antibacterial against Staphylococcus aureus bacteria. The extracts of breadfruit
leaves formulated became ointment that made practice to used. The combine of ointment bases can
obtain of good consistency like the combine of adeps lanae with vaselin album and cera flava with
vaselin album. The aims of this study to know the profile of antibacterial activity of the breadfruit
leaves extract ointment with two kind of the combine of ointment bases. The breadfruit leaves
extract has obtained by maceration method used etanol 70% solvents. The breadfruit leaves
ointment was made by melting method with combination bases A is adeps lanae:vaselin album as
F1 (13.5%:76.5%), F2 (45%:45%) dan F3 (76.5%:13.5%), while combination B is cera
alba:vaselin album as F1 (85.5%:4.5%), F2 (81%:9%), F3 (76.5%:13.5%). antibacterial activity
assay was used well diffusion method and analyzed descriptively. The research result that the all
formulas has breadfruit flavor, smooth texture and brown color. Two variatons of combination
bases ointment has antibacterial activity against Staphylcoccus aureus bacteri with formed of
inhibition zone around the well.
Keywords: Breadfruit leaves extract, ointment, antibacterial, combination of ointment bases