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July 15, 2025
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May 1, 2026
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Abstract

The COVID-19 pandemic continues, and vaccination initiatives are still underway. Booster vaccinations are administered to enhance antibodies that decline after several months of receiving the primary vaccine doses. It is important to understand the impact of these vaccinations on recipients' quality of life. This study aims to examine the influence of demographic and clinical characteristics on the quality of life of the population in Palu City who received the Pfizer® COVID-19 booster vaccine. This research is an observational, cross-sectional study. The sampling was conducted using the consecutive sampling method, and a total of 400 individuals who met the inclusion criteria were included as the sample. This study used the Short Form-8 questionnaire to assess quality of life. Data analysis was performed using multiple linear regression. The study found that the quality of life of individuals who received the Pfizer® COVID-19 booster vaccine in Palu City was good, as evidenced by average domain scores≥50. An individual's quality of life can be assessed in terms of physical and mental aspects. Post-vaccination symptoms and a history of COVID-19 infection (p<0.05) influenced the physical aspect. Age, occupation, and a history of COVID-19 infection (p<0.05) influenced the mental aspect. The quality of life of the population in Palu City who received the Pfizer® COVID-19 booster vaccine showed a greater improvement in mental health than in physical health.

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References

  1. Angeli, F., Reboldi, G., Trapasso, M., Santilli, G., Zappa, M., and Verdecchia, P. (2022). Blood Pressure Increase following COVID-19 Vaccination: A Systematic Overview and Meta-Analysis. Journal of Cardiovascular Development and Disease; 9; 150; 1-9. doi: 10.3390/jcdd9050150.
  2. ASPE. (2022). Demographic Characteristics of Adults Receiving COVID-19 Booster Vaccinations. Asistant Secretary for Planning and Evaluation: USA.
  3. Bruyère, O., Marlens, G., Demonceau, C., Urhausen, A., Seil, R., Leclerc, S., Garrec, S.L., Van, P.L., Edouard, P., Tscholl, P.M., Delvaux, F. Toussaint, J.F., and Kaux, J.F. (2023). Impact of COVID-19 Vaccination on Short-Term Perceived Change in Physical Performance among Elite Athletes: An International Survey. Journal Vaccines; 11; 796; 1-12. doi: 10.3390/vaccines11040796.
  4. Chang, W. (2020). A Review of Vaccine Effects On Women In Light Of The COVID-19 Pandemic. Taiwanese Journal of Obstetrics & Gynecology; 59; 812-820. doi: 10.1016/j.tjog.2020.09.006.
  5. Chaudhuri, K and Howley, P. (2022). The Impact of COVID-19 Vaccination for Mental Well-Being. European Economic Review; 150; 1-8. doi: 10.1016/j.euroecorev.2022.104293.
  6. Chen, I. H., Wu, P.L., Yen, C.F., Ullah, I., Shoib, S., Zahid, S.U., Bashir, A., Iqbal, N., Addo, F.M., Adjaottor, E.S., Amankwaah, G.B., Ahorsu, D.K., Griffiths, M.D., Lin, C.Y., and Pakpour, A.H. (2022). Motors of COVID-19 Vaccination Acceptance Scale (MoVac-COVID19S): Evidence of Measurement Invariance Across Five Countries. Risk Management and Healthcare Policy; 15; 435-445. doi: 10.2147/RMHP.S351794.
  7. Chourpiliadis, C., Lovik, A., Kahler, A. K., Valdimarsdottir, U. A., Frans, E. M., Nyberg, F., Sullivan, P. F., & Fang, F. (2023). Short-term improvement of mental health after a COVID-19 vaccination. Journal Pone. doi: 10.1371/journal.pone.0280587.
  8. Chung, G. K. K., Strong, C., Chan, Y. H., Chung, R. Y. N., Chen, J. S., Lin, Y. H., Huang, R. Y., Lin, C. Y., & Ko, N. Y. (2022). Psychological Distress and Protective Behaviors During the COVID-19 Pandemic Among Different Populations: Hong Kong General Population, Taiwan Healthcare Workers, and Taiwan Outpatients. Front Med. 2022; 9; 1-10. doi: 10.3389/fmed.2022.800962.
  9. Endey, J., Gunawan, P. W., & Dewi, L. V. I. (2024). Uji Kualitas Hidup Pasien Post Vaksinasi COVID-19 dengan Pendekatan SF-36 dan SF-12. Jurnal Mandala Pharmacon Indonesia, 10(1), 98-110. https://doi.org/10.35311/jmpi.v10i1.482
  10. Garcia, P., Anand, S., Han, J., Montez-Rath, M., Sun, S., Parsonet, J., Chertow, G. M., Schiller, B., & Abra, G. (2022). COVID-19 Vaccine Type and Humoral Immune Response in Patients Receiving Dialysis. 022. Journal of the American Society of Nephrology; 33; 33-37. doi: 10.1681/ASN.2021070936
  11. Ghazy, R. M., Fiidow, O. A., Abdullah, F. S. A., Elbarazi, I., Ismail, I. I., Alqutub, S. T., Bouraad, E., Hammouda, E.A., Tahoun, M. M., Mehdad, S., Ashmawy, R., Zamzam, A., Elhassan, O. M., Al Jahdhami, Q. M., Bouguerra, H., Rebai, W. K., Yasin, L., Jaradat, E. M., Elhadi, Y. A. M., & Sallam, M. (2022). Quality Of Life Among Health Care Workers in Arab Countries 2 Years After COVID-19 Pandemic. Frontiers In Public Health. doi: 10.3389/fpubh.2022.91712.
  12. GINA. (2021). GINA Guidance About COVID-19 and Asthma. California: Global Initiative for Asthma.
  13. Goldberg, Y., Mandel, M., Bar-On, Y. M., Bodenheimer, O., Freedman, L., Haas. E. J., Milo, R., Alroy-Preis, S., Ash, N., & Huppert, A. (2021). Waning Immunity after the BNT162b2 Vaccine in Israel. The New England Journal of Medicine; 1-10. doi: 10.1056/NEJMoa2114228.
  14. Haris, R. N. H., Makmur, R., Andayani, T. M., dan Kristina, S. A. (2019). Penilaian Properti Psikometrik Instrumen Kualitas Hidup (HRQoL) pada Populasi Umum: Tinjauan Sistematik. JMPF, 9(2), 65-75. Doi: 10.22146/jmpf.41911.
  15. Kemenkes RI. (2020). Keputusan Menteri Kesehatan RI No. HK.01.07/MENKES/9860/2020 Tentang Penetapan Jenis Vaksin Untuk Pelaksanaan Vaksinasi Coronavirus Disease 2019 (COVID-19). Jakarta: Kemenkes RI.
  16. Khoury, J., Najjar-Debbiny, R., Hanna, A., Jabbour, A., Ahmad, Y. A., Saffuri, A., Abu-Sinni, M., Shkeiri, R., Elemy, A., & Hakim, F. (2021). COVID-19 vaccine – Long term immune decline and breakthrough infections. Journal Vaccine; 39; 6984-6989. doi: 10.1016/j.vaccine.2021.10.038.
  17. Laar, R.A., Zhang, Z., Menhas, R., Zhang, L., Zhu, S., Fan, X., Wang, W., and Li, S. (2022). Impact of Coronavirus Disease of 2019 Vaccine on Health and Physical Activities Among Physical Education Students in China. Frontiers in Public Health; 10; 1-11. doi: 10.3389/fpubh.2022.889311.
  18. Lai, C. C., Shih, T. P., Ko, W. C., Tang, H. J., & Hsueh, P. R. (2020). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. International Journal of Antimicrobial Agents; 55; 1-9. doi: 10.1016/j.ijantimicag.2020.105924.
  19. Lang, L., Zhang, L., Zhang, P., Li, Q., Bian, J., and Guo, Y. (2018). Evaluating The Reliability And Validity of Short Form-8 With A Large Representative Sample Of Urban Chinese. Biomed Central; 16; 55; 1-8. doi: 10.1186/s12955-018-0880-4.
  20. Lee, S.E., Shim, S.R., Youn, J.H., and Han, H.W. (2023). COVID-19 Vaccination Is Not Associated with Psychiatric Adverse Events: A Meta-Analysis. Journal Vaccines; 11; 194; 1-12. doi: 10.3390/ vaccines11010194.
  21. Lin, C. Y., Fan, C. W., Ahorsu, D. K., Lin, Y. C., Weng, H. C., and Griffiths, M. D. (2022). Associations Between Vaccination And Quality Of Life Among Taiwan General Population: Acomparison Between COVID-19 Vaccines And Fluvaccines. Human Vaccines and Immunotherapeutics; 18; 05; 1-8. doi: 10.1080/21645515.2022.2079344.
  22. Mathioudakis, A. G., Ghrew, M., Ustianowski, A., Ahmad, S., Borrow, R., Papavasileiou, L. P., Petrakis, D., and Bakerly, N. D. (2021). Self-Reported Real-World Safety and Reactogenicity of COVID-19 Vaccines: A Vaccine Recipient Survey. Journal Life; 11; 1-13. doi: 10.3390/life11030249.s
  23. Menni, C., May, A., Polidori, L., Louca, P., Wolf, J., Capdevila, J., Hu, C., Ourselin, S., Steves, C. J., & Valdes, A. M. (2022). COVID-19 Vaccine Waning and Effectiveness and Side-Effects of Boosters: A Prospective Community Study From The ZOE COVID Study. doi: 10.1016/S1473-3099(22)00146-3. Lancet Infect Disease; 22; 1002-1010. Doi: 10.1016/ S1473-3099(22)00146-3
  24. MENPAN. (2022). Diperoleh dari website Kementerian Pendayagunaan Aparatur Negara dan Reformasi Birokrasi: https://menpan.go.id/site/berita-terkini/reisa-vaksin-booster-tingkatkan-proteksi-individu. Accessed: 17 Februari 2022.
  25. Ministry Of Health Uganda. (2021). COVID-19 Vaccine Frequently Asked Questions: What You Need to Know. Uganda: Ministry of Health Uganda.
  26. Ophinni, Y., Hasibuan, A. S., Widhani, A., Maria, S., Koesnoe, S., Yunihastuti, E., Karjadi, T. H., Rengganis, I., & Djauzi, S. (2020). COVID-19 Vaccines: Current Status and Implication for Use in Indonesia. Acta Med Indones - Indones J Intern Med; 52; 4; 388-412.
  27. Pinzon, R. T., Adnyana, K. S. G., dan Zalukhu, M. L. (2017). The Profile and Determinant Factors of Quality of Life in Patients with Diabetic Neuropathy. National Public Health Journal; 12; 1; 38-42. doi: 10.21109/kesmas.12i1.1252.
  28. Romero-Brufau, S., Chopra, A., Ryu, A. J., Gel, E., Raskar, R., Kremers, W., Anderson, K. S., Subramanian, J., Krishnamurthy, B., Singh, A., Pasupathy, K., Dong, Y., O’Horo, J. C., Wilson, W. R., Mitchell, O., & Kingsley, T. C. (2021). Public Health Impact of Delaying Second Dose of BNT162b2 or mRNA-1273 Covid-19 Vaccine: Simulation Agent Based Modeling Study. British Medical Journal. doi: 10.1136/bmj.n1087.
  29. Rondunuwu, M. (2021). Buku Saku: Tanya Jawab Seputar Vaksinasi COVID-19. Jakarta: Direktur Jenderal Pencegahan dan Pengendalian Penyakit.
  30. Saeidi, M. (2022). COVID-19 Vaccine Injection Technique and Considerations for Health Providers. Health Provid; 1; 103-106. doi: 10.22034/hp.2022.355133.1021
  31. Suryonegoro, S. B., Elfa, M. M., dan Noor, M. S. (2022). Hubungan Hipertensi pada Wanita Menopause dan Usia Lanjut terhadap Kualitas Hidup. Jurnal Homeotasis; 4; 2; 387-398.
  32. Wulandari, A., Rahman, F., Pujianti, N., Sari, A. R., Laily, N., Anggraini, L., Muddin, F. I., Ridwan, A. M., Anhar, V. Y., Azmiyannoor, M., & Prasetio, D. B. (2020). Hubungan Karakteristik Individu dengan Pengetahuan tentang Pencegahan Coronavirus Disease 2019 pada Masyarakat di Kalimantan Selatan. Jurnal Kesehatan Masyarakat Indonesia; 15; 1; 42-46.